Clarity Clinical Trial
Patients with Uveitis (open for recruitment)
This is a clinical trial aiming to look at the safety and effects of an investigational medication taken by mouth to treat uveitis. Uveitis is a condition involving inflammation of the uvea, the layer of the eye between the inner and outer part of the eye.
This study is for adults with active, non-infectious, intermediate/posterior/pan-uveitis.
Meerkat UME Clinical Trial
Patients with Uveitic Macular Edema (closed for recruitment)
We are conducting a clinical trial to evaluate a product called RO7200220 for patients with uveitic macular edema (UME), a complication of acute or chronic uveitis.
UME causes fluid to accumulate in the tissue around the retina. The retina is the part inside the back of the eye which senses light and allows you to see. Accumulated fluid causes damage to the layers of the retina and can cause vision loss. UME can impair performance of activities such as driving, reading, recognizing faces, and other fine details of daily living. In the advanced stage of the disease, UME can result in severe vision loss or blindness.
Currently available therapies for the treatment of UME may improve vision over time but are associated with significant adverse effects. There is an unmet need for effective non‑steroidal therapies for UME. The purpose of this study is to evaluate the safety and efficacy of RO7200220 intravitreal injections in participants with UME compared to sham control.