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OSU Researchers Receive R01 Grants  


The Ohio State University Medical Center is pleased to announce that Jiyan Ma, Associate Professor of Molecular and Cellular Biochemistry, and Min Zhou, Assistant Professor of Neuroscience will be the recipients of the National Institutes of Health’s (NIH) Research Project Grant (R01).

Ma will be receiving $1.7 million from the National Institute Neurological Disorders and Stroke (NINDS) for his interest in what causes a particular group of infectious agents, or proteins, to transmit disease. Specifically, Ma will be studying what causes the prion protein to form different strains that lead to the development of prion disease, a condition that affects the nervous system and impairs brain function.

Zhou is the recipient of a $1.3 million grant, also from NINDS, to fund research in hopes of better understanding the role a specific type of brain cell plays in the pathology of strokes. In this study, Zhou will be investigating a new type of potassium channel, a two-pore domain K + channel, in astrocytes, which are the most numerous brain cells strategically situated between blood vessels and neurons that act as transporters within the brain. According to Zhou, the research is important for identifying new opportunities to examine astrocytes and potassium channel expression that helps astrocytes, as well as neurons, survive stroke.

The Research Project Grant is the original and historically oldest grant mechanism used by the NIH. Specifically, the RO1 grant is an award made to support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing the investigator’s specific interest and competencies, based on the mission of the NIH.

The largely application-based R01 grant seeks to provide support for health-related research. While there are no specific requirements, the R01 research plan proposed must be related to one or more NIH Institutes and Centers, stated program interests. The NIH is comprised of Institutes and Centers that support specific areas of health-related research and almost all Institutes and Centers at the NIH fund R01 grants. Research grant applications are assigned to an Institute or Center based on receipt and referral guidelines, and many applications are assigned to multiple Institutes and Centers, as interdisciplinary and multidisciplinary research is encouraged.

Please join us in congratulating Jiyan Ma and Min Zhou for their hard work and dedication. Learn more about the NIH Research Grant Program and view a complete list of NIH Institutes and Centers.

Click here to view a video of Jiyan Ma discussing his research.

Click here to view a video of Min Zhou discussing his research.


Posted on 15-Nov-11 by Geier, Eric
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