The Comprehensive Cardiovascular Biorepository (CCB) directs and maintains a collection of thousands of human cardiothoracic tissue samples provided by consenting patients who have a cardiovascular disease.

The CCB, part of The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine, processes, stores and distributes biospecimens for cardiovascular research.

Our services

We provide researchers access to high-quality and clinically annotated tissue biospecimens to facilitate new translational research, new diagnostics, new therapeutics, quality improvement and future opportunities for multi-institution collaborative research.

Collected samples available for approved research projects include, but are not limited to:

  • Fresh and frozen tissue
  • Plasma (frozen vial)
  • Serum (frozen vial)
  • Whole blood (frozen vial)

Request samples

You must have Ohio State Institutional Review Board (IRB) approval to request samples.

To request samples, complete this form:


Item Cost
Annual Cardiovascular Biorepository Fee $5,000
10% Formalin or 4% Paraformaldehyde $300
AllProtect (protects RNA, DNA and protein in tissue) $300
Consenting (per patient) $150
Data Request Tech Time (per 15 min) $50
Flash Frozen or Frozen on dry ice or stored sample $240
Fresh on ice (in incomplete media or saline) $2,500
Generic cardiac clinical data/sample $100
Patient Screening (per patient) $50
PBMCs Frozen/vial $500
PI Specific data abstraction $80
RNAlater (protects RNA, DNA and protein in tissue) $300
Scientific Review Application fee $500
Serum/plasma frozen $300
Specialty Sample Collection (additional cost added to tissue cost) $500
Storing of samples (per box/year) $250
Study Initiation Fee $500
Tech Time (per hour) $150

Our Team

Richard Gumina, MD, PhD

Richard Gumina, MD, PhD

  • Director, Comprehensive Cardiovascular Biorepository

Xun Ai, MD

  • Director, Cardiovascular Tissue Repository
    Provides day-to-day operational oversight and direction of the cardiovascular tissue repository in consultation with the Associated Dean of Convergent Research and the director of the Dorothy M. Davis Heart and Lung Research Institute (DHLRI).
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Hannah Lindsay

  • Biorepository Manager

CCB Executive Committee

The CCB Executive Committee will meet quarterly, or as needed, ensuring sustainability and compliance. Its members are:

CCB Scientific Review Committee

The Scientific Review Committee will meet quarterly, or as needed, to review and prioritize researcher requests. Recommendations for prioritization of collection will be delivered to the executive committee for final decision, and capacity to satisfy specific requests will be communicated to requesters via email.

The Scientific Review Committee members will be nominated by the Biorepository director and/or the vice dean of Convergent Research for final approval by the Executive Committee with broad representation from main constituents (Surgery, CVM, PCB, DHLRI). Appointments will be reviewed annually and subject to termination at any time, with or without cause, by the Executive Committee. Charter members of the Scientific Review Committee are: Kristin Stanford, PhD (DHLRI), Sakima Smith, MD (CVM), and Matthew Henn, MD (Surgery).