The research we perform at the Ohio State Comprehensive Transplant Center covers basic, translational and clinical, with the goal of developing the next generation of surgical innovation. What we learn at the bench we apply to the bedside.
Current Research Studies
Heart Transplant Research
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Heart EXPAND Continued Access Protocol
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Organ Care System (OCS) for Hearts from DCD
Lung Transplant Research
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(BOSTON-1) Liposomal Cyclosporine A for BOS
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(BOSTON-2) Liposomal Cyclosporine A for BOS
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Cardiopulmonary Exercise Testing
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Donor Quality Study
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Ex Vivo Lung Perfusion (EVLP)
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Extracorporeal Photopheresis for Medicare Recipients
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Novel Markers of Human Lung Disease
Kidney Transplant Research
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AlloSure: KOAR
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APOL1: Kidney
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BK Viremia in Kidney Recipients
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Cellular Immunotherapy in Recipients of HLA-matched, Living Donor Kidney Transplants
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FCR001 Cell Therapy
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Fecal Microbiota Transplantation
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Immunocompromised Infections Study Protocol
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Letermovir vs. Valganciclovir for Prevention of CMV in Kidney Transplant Recipients
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Long Term Outcomes of Living Donation or ALTOLD
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BB3 to Reduce Delayed Graft Function
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QPI-1002 for Prevention of Delayed Graft Function
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Cinryze® for the Treatment of Acute Antibody-Mediated Rejection
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Sirolimus and Everolimus in Combination with Low Dose Cyclosporine
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Comparing Everolimus and Sirolimus in Renal Transplant Recipients
Liver Transplant Research
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Acute Liver Failure
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13C-Methacetin Breath Test
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Hemostatic Abnormalities
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Portable Organ Care (OCS™) System for DCD Liver Donors
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OCS® Liver PROTECT Trial
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Quantitation of HCV RNA
Islet Transplant Research
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Islet Allotransplantation in Type 1 Diabetes
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Collaborative Islet Transplant Registry
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Advancing Treatment for Pancreatitis
Active Research Grants
Active and pending grants
- Ginny Bumgardner MD, PhD – Advanced research training in immunology for surgery trainees (ARTIST), National Institutes of Health (NIH, NIAID), 8/1/2019 - 7/31/2024, $1,600,000
- Ginny Bumgardner MD, PhD – NIH RO1 grant investigating a novel cellular therapy to prevent and treat acute antibody mediated kidney transplant rejection - 7/2019 - 7/2024, $2,686,090
- Ginny Bumgardner MD, PhD – TL1 NIH grant advancing today's discoveries to improve health - 6/2019 - 5/2020, $258,712
- Bryan Whitson, MD, PhD – NIH RO1 grant investigating preservation and rescue of the lung donor allograft for transplantation, 7/1/2018 - 6/30/2023, $3,472,273
- Bryan Whitson, MD, PhD – Developing MG53 as a novel protein therapeutic for acute lung injury, Department of Defense, 7/1/2018 - 6/30/2021, $3,696,579
- Bryan Whitson, MD, PhD and Sylvester Black, MD, PhD - Accelerator Award, $150,000
- Sylvester Black, MD, PhD – Muscle-liver crosstalk via the myokine MG53 plays a critical role in hepatocellular protection, NIH RO1 NIDDK, 3/1/2020 - 3/1/2025, $3,200,000 - read more
- Austin Schenk, MD, PhD – TCR repertoire, specificity, and the endothelial barrier in allograft rejection and tolerance, American Heart Association Career Development Award, 4/1/2019 -3/31/2022, $231,000
Recently completed grants
- Sylvester Black, MD, PhD - Hepatic Stellate Cell Mediation of Ischemia Reperfusion Injury in Liver Transplantation, The Ohio State University Department of Surgery Faculty Development Grant, 1/2017 - 1/2019, $25,000 per year for two years
- Ginny Bumgardner MD, PhD - Advanced research training in immunology for surgery trainees (ARTIST), National Institutes of Health (NIH, NIAID), 8/15/2014 - 7/31/2019, $728,445
- Jason Zimmerer PhD, Ginny Bumgardner MD, PhD - DOS Lockwood Early Career Development Award, Investigation of Cytokine Gene Polymorphisms, T Cell Profiles and Alloantibody Levels and Isotypes from Peripheral Blood in Primary Kidney Transplant Patients, 11/5/2014 - 11/5/2017, $25,000
- Ginny Bumgardner MD, PhD - Novel mechanisms regulating post-transplant alloantibody productions, NIH RO1, 9/1/2011 - 8/31/2016, $1,527,967
- Ginny Bumgardner MD, PhD - Demographic and Clinical Factors and Transplant Outcomes Associated with Hospital Readmissions within the First Year after Kidney Transplantation in Adult Recipients, OSU Comprehensive Transplant Center, 05/30/2015 - 12/30/2016