Improving patients' lives through research
Research holds a place of prominence in the Department of Internal Medicine. In keeping with the overall mission of The Ohio State University Wexner Medical Center to “improve patients’ lives through research,” the department has a committed faculty of clinical, translational and basic scientists working to discover breakthroughs to end human suffering.
Clinical Trials
The Division of Gastroenterology, Hepatology, and Nutrition conducts a variety of clinical trials, including investigator initiated, NIH-sponsored, multi-center, and investigational drug/device trials. The Division has over 30 active clinical trials in the following areas:
- (Recurrent) Acute Pancreatitis
- Chronic Pancreatitis
- Diabetes Mellitus
- Crohn’s Disease
- Ulcerative Colitis
- Short Bowel Syndrome
- Pancreatic Cancer
- Hepatitis C
- Non-Alcoholic Steatohepatitis
- Acute Liver Injury/Failure
- End-Stage Liver Disease
- Hepatorenal Syndrome Type 1
- Cystic Pancreatic Lesions (Pancreas Cysts)
- Total Pancreatectomy with Islet Autotransplantation (TPIAT)
- Pancreatic Necrosectomy
- Decompensated Cirrhosis
- Primary Biliary Cholangitis and Hepatic Impairment
- Achalasia and Other Motility Disorders
For more information regarding current clinical trials, please email GHNResearch@osumc.edu.
Recent Publications
Race and Gender Differences in Chronic Pancreatitis (CP): Analysis of Nationwide Inpatient Sample (NIS) from 2003 to 2011- Jennifer Behzadi, Darwin L. Conwell, Alice Hinton, Somashekar G. Krishna
Type 2 Diabetes Mellitus Increases Economic Burden of Colorectal Cancer Surgery - Hisham Hussan, Darrell M. Gray, Somashekar G. Krishna, Alice Hinton, Jeffery R. Groce, Darwin L. Conwell, Peter P. Stanich
Diabetes is Associated with Socioeconomic Disparities and More Co-morbidities in Colorectal Cancer Surgery - a Nationwide Inpatient Sample Study -Hisham Hussan, Peter P. Stanich, Darwin L. Conwell, Samer El-Dika, Somashekar G. Krishna, Alice Hinton, Darrell M. Gray
A High Body Mass Index (BMI) is Associated with Incremental Health Care Utilization and Surgical Complications in Patients Undergoing Colorectal Cancer Surgery - Hisham Hussan, Darrell M. Gray, Cheng Zhang, Alice Hinton, Somashekar G. Krishna, Sheetal Sharma, Darwin L. Conwell, Peter P. Stanich
Groove Pancreatitis, a masquerading yet distinct clinicopathological entity: Analysis of Risk Factors and Differentiation -Veeral M. Oz1, Jacob M. Skean1, Peter Muscarella, Brett C. Sklaw, Kevin M. Cronley, Jon Walker, Samer El-Dika, Benjamin Swanson, Alice Hinton, Darwin L. Conwell, Somashekar G. Krishna
Early Naso-Enteral Tube (NET) is Associated with Higher Mortality Compared to Early PEG Tube in Stroke Patients Admitted with Dysphagia in the United States -Samer S. El-Dika, Somashekar G. Krishna, Jeffery R. Groce, Peter P. Stanich, Hisham Hussan, Alice Hinton, Darwin L. Conwell
Efficacy of Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA) in Obtaining Optimal Samples for Immunohistochemistry (IHC) in Pancreatic Ductal Adenocarcinoma (PDA) - Reshi Kanuru MD, Michael Wellner MD, Ming Jin MD, Kyle Porter MAS, Jon P Walker MD, Somashekar Krishna MBBS MPH, Adrian Suarez MD, and Samer El-Dika MD MS
The Increasing Prevalence of Human Cytomegalovirus (CMV) Disease Among Hospitalized Patients with Inflammatory Bowel Disease (IBD) in the United States - Cheng Zhang, Edward J. Levine, Somashekar G. Krishna, Alice Hinton, Darwin Conwell, Razvan Arsenescu
Health Outcomes of Ulcerative Colitis (UC) and Crohn’s Disease (CD) Patients Hospitalized with Human Cytomegalovirus (CMV) Disease - Cheng Zhang, Edward J. Levine, Somashekar G. Krishna, Alice Hinton, Darwin Conwell, Razvan Arsenescu
Acute pancreatitis (AP) in post-bariatric surgery (BRS) status: Analysis of national trends, complications and outcomes from 2007 to 2011 - Somashekar G. Krishna, Jennifer Behzadi, Alice Hinton, Samer El-Dika, Jeffery R. Groce, Hisham Hussan, Darwin L. Conwell
The Impact of Sphincter of Oddi Dysfunction (SOD) on Health Care Utilization in Patients Admitted for Abdominal Pain - Jeffery R. Groce, Somashekar G. Krishna, Samer El-Dika, Sheetal Sharma, Alice Hinton, Darwin Conwell
Biliary intervention after bariatric surgery (BRS): Inferences from a nationwide population-based study - Somashekar G. Krishna, Alecia Blaszczak, Samer El-Dika, Jeffery R. Groce, Hisham Hussan, Cheng Zhang, Jeffrey Wenzke, Sheetal Sharma, Darwin L. Conwell
Morbid Obesity (MO) is Associated with Increased Healthcare Utilization and is an Independent Predictor of Mortality of Acute Pancreatitis (AP) - Somashekar G. Krishna, Samer El-Dika, Alice Hinton, Jeffery R. Groce, Hisham Hussan, Cheng Zhang, Peter P. Stanich, Na Li, Darwin L. Conwell
Diverticulitis in HIV/AIDS Patients is Associated with Increased Mortality - Kevin M. Cronley, Jeffrey Wenzke, Hisham Hussan, Alice Hinton, Darwin L. Conwell1, Somashekar G. Krishna, Peter P. Stanich
Video Capsule Endoscopy is Safe and Effective in Hospitalized Patients with Implantable Cardiac Devices and Left Ventricular Assist Devices - John M Guido MD, Peter P Stanich MD, Bryan Kleinman DO, Nishaki Mehta Oza MD, Kavita Betkerur BS, Kyle Porter MS and Marty M Meyer MD
Video capsule endoscopy completion rates and total transit times are similar with oral or endoscopic delivery - John Guido MD, Peter P Stanich MD, Bryan Kleinman DO, Kavita Betkerur BS, Kyle M Porter MS and Marty M Meyer MD
Prevalence and severity of cytopenias in hospitalized patients with cirrhosis - Brett Sklaw, Eric Kraut
Protocol for Coronary Artery Disease Screening among Orthotopic Liver Transplant Candidates - Bryan Lee, Feng Li, Scott M. Lilly, A. James Hanje
Pre-transplant characteristics in patients evaluated for orthotopic liver transplant (OLT) associated with positive stress test - Feng Li, Bryan Lee, Kyle Porter, Nicole O'Bleness, Scott M. Lilly, A. James Hanje
Post-transplant cardiac events among patients receiving orthotopic liver transplant (OLT) - Feng Li, Bryan Lee, Kyle Porter, Nicole O'Bleness, Scott M. Lilly, A. James Hanje
Use of Bayesian Analysis to Predict Pancreatic Fibrosis with the Secretin Endoscopic Pancreatic Function Test (ePFT): Comparison to Histopathology Gold Standards – Feng Li, Wendy Frankel, Alice Hinton, Philip Hart, Darwin Conwell
Derivation of a Non-invasive, Chronic Pancreatitis (CP) Risk Score- Darwin L. Conwell, Linda S. Lee, Vivek Kadiyala, Shadeah Suleiman, Peter Banks
Urban Hospitalization Increases Costs and Healthcare Utilization for Diverticulitis in the United States – Sheryl Pfeil, Kyle Porter, Darwin Conwell
Gender disparities of acute liver injury in the United States: analysis of the National Inpatient Sample from 2006-2011- Na Li, Alice Hinton, Somashekar Krishna, James Hanje, Darwin Conwell
A Case of Mistaken Identity: Disseminated Bartonella as Pancreatic Mass – Jennifer Behzadi, Mohamed S. Naem, Somashekar G. Krishna
Iatrogenic Superior Mesenteric Arterio-venous Fistula as an Unusual Cause of Refractory Ascites: A Case Report – Jager Jasem, Jean R. Park, Gabriel C. Lockhart, A. James Hanje
Ovarian Cancer Metastatic to the Stomach: A “Reverse Krukenberg” Tumor – John M. Guido, MD, Peter P. Stanich, MD, Edward Levine, MD
Ovarian Cancer Despite Previous Oophorectomy in Liver Transplant Patient – Jennifer Behzadi, MD, Peter P. Stanich, MD, and Robert Kirkpatrick, MD
Intraoperative enteroscopy remains a useful modality in obscure gastrointestinal bleeding – Feng Li, Jeffrey Kuo, Samer El-Dika, Marty Meyer, Peter Stanich
Broncho-esophageal Fistula: Imaging versus Endoscopy – Reshi Kanuru, MD, Someshakar Krishna, MD, and Peter Stanich, MD
Recurrent acute pancreatitis following Roux-en-Y gastric bypass (RYGB): The afferent loop syndrome – Feng Li, Jonathan Congeni, Somashekar G. Krishna
Gastrostomy tube migration causing acute pancreatitis – Feng Li, Mohamed S. Naem, Cheng Zhang, Somashekar G. Krishna