Synthesizing and distilling evidence to shape clinical practice, inform health policy, and drive future research
Since 1997, the RTI-UNC Evidence-based Practice Center (EPC) has produced original and update systematic reviews of the scientific evidence on a variety of health care and health policy topics, from prevention and screening through diagnostic testing to therapy, rehabilitation, counseling, and palliative care.
What the RTI-UNC Evidence-based Practice Center focuses on
Based on systematic reviews and syntheses of the scientific evidence, the EPC prepares reports and technology assessments for the U.S. Preventive Services Task Force (USPSTF), the Agency for Healthcare Research and Quality (AHRQ) Effective Health Care (EHC) and Technology Assessment Programs, the Drug Effectiveness Review Project (DERP), the Washington State Health Technology Assessment (WA-HTA), and other public and private health care organizations.
Who we are
The EPC is a collaborative effort between Ohio State University Wexner Medical Center and RTI International, drawing extensive assets from five significant clinical and public health areas (dentistry, medicine, nursing, pharmacy, and public health), combining expertise in research and policy analysis with a depth of technical skills in all forms of quantitative, qualitative, and social sciences methodology.
Our team members bring decades of experience in conducting systematic reviews using an interdisciplinary approach that allows for a thorough examination of topics from a broad perspective. Going to edit this to gear more towards OSU GIM.
Projects by the RTI-UNC Evidence-based Practice Center involving OSU Contributors
Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis
2023 | JAMA | JAMA
McPheeters M, O’Connor EA, Riley S, et al. 2023;330(17):1653–1665. doi:10.1001/jama.2023.19761
Screening for Latent Tuberculosis Infection in Adults: An Evidence Review for the U.S. Preventive Services Task Force
May 2023 | U.S. Preventive Services Task Force | USPSTF
Jonas DE, Riley S, Lee L, Coffey C, Wang SH, Asher G, Berry A, Williams N, Balio C, Voisin CE, Kahwati L. Screening for Latent Tuberculosis Infection in Adults: An Evidence Review for the U.S. Preventive Services Task Force. Evidence Synthesis No. 226. AHRQ Publication No. 22-05298-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2023.
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Serological Screening for Genital Herpes: A Reaffirmation Evidence Update for the U.S. Preventive Services Task Force
February 2023 | U.S. Preventive Services Task Force | USPSTF
Asher GN, Feltner C, Harrison WN, Schwimmer M, Rains C, Jonas DE. Serological Screening for Genital Herpes: A Reaffirmation Evidence Update for the U.S. Preventive Services Task Force. Evidence Synthesis No. 224. AHRQ Publication No. 22-05296-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2023.
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Screening for Obstructive Sleep Apnea in Adults: An Evidence Review for the U.S. Preventive Services Task Force
November 2022 | U.S. Preventive Services Task Force | USPSTF
Feltner C, Wallace IF, Aymes S, Middleton JC, Hicks KL, Schwimmer M, Baker C; Balio CP, Moore D, Voisin CE, Jonas DE. Screening for Obstructive Sleep Apnea in Adults: An Evidence Review for the U.S. Preventive Services Task Force. Evidence Synthesis No. 222. AHRQ Publication No. 22-05294-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2022.
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Hormone Therapy in Postmenopausal Persons: Primary Prevention of Chronic Conditions
November 2022 | U.S. Preventive Services Task Force | USPSTF
Gartlehner G, Patel SV, Reddy S, Rains C, Coker-Schwimmer M, Kahwati L. Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: An Evidence Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2022 Nov. Report No.: 22-05294-EF-1. PMID: 36413605.
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Screening for Prediabetes and Type 2 Diabetes Mellitus in Children and Adolescents: An Evidence Review for the U.S. Preventive Services Task Force
September 2022 | U.S. Preventive Services Task Force | USPSTF
Jonas DE, Vander Schaaf EB, Riley S, Allison BA, Middleton JC, Baker C, Ali R, Voisin CE, LeBlanc ES. Screening for Prediabetes and Type 2 Diabetes Mellitus in Children and Adolescents: An Evidence Review for the U.S. Preventive Services Task Force. Evidence Synthesis No. 216. AHRQ Publication No. 21-05288-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2022 September.
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Screening for Glaucoma in Adults: A Systematic Review for the U.S. Preventive Services Task Force
May 2022 | U.S. Preventive Services Task Force | USPSTF
Chou R, Selph SS, Blazina I, Bougatsos C, Jungbauer R, Fu R, Grusing S, Jonas D, Tehrani S. Screening for Glaucoma in Adults: A Systematic Review for the U.S. Preventive Services Task Force. Evidence Synthesis No. 214. AHRQ Publication No. 21-05286-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2022 May.
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Screening for Impaired Visual Acuity in Older Adults: A Systematic Review for the U.S. Preventive Services Task Force
May 2022 | U.S. Preventive Services Task Force | USPSTF
Chou R, Bougatsos C, Jungbauer R, Grusing S, Blazina I, Selph SS, Jonas D, Tehrani S. Screening for Impaired Visual Acuity in Older Adults: A Systematic Review for the U.S. Preventive Services Task Force. Evidence Synthesis No. 213. AHRQ Publication No. 21-05285-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2022 May.
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Stop Unhealthy (STUN) Alcohol Use Now trial
April 2022 | AHRQ via R18 funding | Implement Res Pract (2021-2022)
Balio CP, Riley SR, Grammer D, Weathington C, Barclay C, Jonas DE. Barriers to recruiting primary care practices for implementation research during COVID-19: A qualitative study of practice coaches from the Stop Unhealthy (STUN) Alcohol Use Now trial. Implement Res Pract. 2022 Apr 24;3:26334895221094297. doi: 10.1177/26334895221094297. PMID: 37091109; PMCID: PMC9924268.
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Stop Unhealthy (STUN) Alcohol Use Now trial
November 2021 | AHRQ via R18 funding | Trials (2021)
Jonas DE, Barclay C, Grammer D, Weathington C, Birken SA, DeWalt DA, Shoenbill KA, Boynton MH, Mackey M, Riley S, Cykert S. The STUN (STop UNhealthy) Alcohol Use Now trial: study protocol for an adaptive randomized trial on dissemination and implementation of screening and management of unhealthy alcohol use in primary care. Trials. 2021 Nov 16; 22(1): 810. PMID 34784953. PMCID: PMC8593635. doi: 10.1186/s13063-021-05641-7.
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Screening for Eating Disorders in Adolescents and Adults: An Evidence Review for the U.S. Preventive Services Task Force
March 2022 | U.S. Preventive Services Task Force | USPSTF
Feltner C, Peat C, Reddy S, Riley S, Berkman N, Middleton JC, Balio C, Coker-Schwimmer M, Jonas DE. Screening for Eating Disorders in Adolescents and Adults: An Evidence Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2022 Mar. Report No. 21-05284-EF-1. PMID: 35344311.
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Screening for Atrial Fibrillation: An Evidence Review for the U.S. Preventive Services Task Force
January 2022 | U.S. Preventive Services Task Force | USPSTF
Kahwati L, Asher GN, Kadro ZO, Keen S, Ali R, Coker-Schwimmer E, Jonas DE. Screening for Atrial Fibrillation: An Evidence Review for the U.S. Preventive Services Task Force. Evidence Synthesis No. 208. AHRQ Publication No. 21-05277-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2022 January.
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Screening for Prediabetes and Type 2 Diabetes Mellitus: An Evidence Review for the U.S. Preventive Services Task Force
August 2021 | U.S. Preventive Services Task Force | USPSTF
Jonas DE, Crotty K, Yun JDY, Feltner C, Taylor-Phillips S, Middleton JC, Barclay C, Dotson A, Baker C, Balio CP, Voisin C, Harris RP. Screening for Prediabetes and Type 2 Diabetes Mellitus: An Evidence Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Aug. Report No.: 21-05276-EF-1. PMID: 34554661.
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Screening for Hearing Loss in Older Adults: An Evidence Review for the U.S. Preventive Services Task Force
March 2021 | U.S. Preventive Services Task Force | USPSTF
Feltner C, Wallace I, Kistler C, Coker-Schwimmer M, Jonas DE, Middleton JC. Screening for Hearing Loss in Older Adults: An Evidence Review for the U.S. Preventive Services Task Force. Comparative Effectiveness Review No. 200. AHRQ Publication No. 20-05269-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2021.
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Screening for Lung Cancer with Low-Dose Computed Tomography: Updated Evidence Report and Systematic Review for the U.S. Preventive Services Task Force
March 2021 | U.S. Preventive Services Task Force | USPSTF #1 | USPSTF #2
Jonas DE, Reuland DS, Reddy SM, Nagle M, Clark SD, Weber RP, Enyioha C, Malo TL, Brenner AT, Armstrong C, Coker-Schwimmer M, Middleton JC, Voisin C, Harris RP. Screening for Lung Cancer with Low-Dose Computed Tomography: An Evidence Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Mar. Report No.: 20-05266-EF-1. PMID: 33750087.
Meza R, Jeon J, Toumazis I, ten Haaf K, Cao P, Bastani M, Han SS, Blom EF, Jonas D, Feuer EJ, Plevritis SK, de Koning HJ, Kong CY. Evaluation of the Benefits and Harms of Lung Cancer Screening With Low-Dose Computed Tomography: A Collaborative Modeling Study for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Mar. Report No.: 20-05266-EF-2. PMID: 33750088.