Kevin Blum in suit sitting outside with dogKevin Blum

Area of Study: Biomedical Engineering, Cardiovascular Regenerative Medicine
Hometown: Fort Wayne, IN

Academics

Research interests

Tissue Engineering, Regenerative Medicine, Biomaterials, Medical Device Design

Awards and Honors

  • 2009-2013 Purdue University Trustee’s Scholarship
  • 2010 Robert C. Byrd Academic Scholarship
  • 2010 Tau Beta Pi Best Active Member
  • 2011 Best Poster Honor at Purdue SURF Research Symposium
  • 2012 Purdue University Dance Marathon: Male Moraler of the Year
  • 2013 Graduated with Distinction (90th percentile), Bachelors of Science in Biomedical Engineering, Purdue University
  • 2014 Charles C. Chappelle Fellowship
  • 2014 Bourland Travel Grant Award
  • 2015 Best Poster Honor at OSU DHLRI Research Day
  • 2016 MSTP Leadership and Academic Scholarship Award
  • 2017 ASCP Academic Excellence and Achievement in Pathology Award
  • 2017 The Ohio State University Graduate School University Fellowship
  • 2017 Special Recognition Poster Honor at Nationwide Children’s Hospital Summer Student Poster Competition
  • 2018 2nd Place Poster Honor in Biomedical Engineering Category at American Physician Scientist Association Midwest Regional Meeting
  • 2018 Poster of Distinction Honor in Graduate/Medical Student Category at Nationwide Children’s Hospital Research Retreat
  • 2019 Edward J. Ray Travel Award for Scholarship and Service
  • 2020 Tau Beta Pi 35th Centennial Fellowship
  • 2020 The Ohio State University Dr. Stuart S. and Letitia Roberts Collaborative Research Award

Patents

  • Grewe D, Blum K, Hadley R (2016) “Steerable Intraluminal Medical Device” US Patent No. 9,364,636
  • Blum K, Sherman S (2017) “Occlusion Device” US Patent No. 9,668,742
  • Novak T, Blum K, Neu C, Voytik-Harbin S (2018) “Collagen Compositions and Methods of Use” US Patent No. 9,878,071
  • Blum K, Milner K, Sherman S (2018) “Layered medical device with improved adhesion and methods of making” US Patent No. 10,076,406

Publications

  • Bijangi-Vishehsaraei K, Blum K, Zhang H, Safa A, Halum S (2016) “Microarray Analysis Gene Expression Profiles in Laryngeal Muscle After Recurrent Laryngeal Nerve Injury” Ann Otol Rhinol Laryngol 125(3):247-56 PMID: 25630091
  • Blum K, Novak T, Watkins L, Neu C, Wallace J, Bart Z, Voytik-Harbin S (2016) “Acellular and Cellular High Density, Collagen-Fibril Constructs with Suprafibrillar Organization” Biomaterial Science 4(4):711-23 PMID: 26902645
  • Gynawali S*, Blum K*, Pal D, Ghatak S, Khanna S, Roy S, Sen C (2017) “Retooling Laser Speckle Contrast Analysis Algorithm to Enhance Non-Invasive High Resolution Laser Speckle Imaging of CutaneousMicrocirculation” Nature Scientific Reports 7:41-48 PMID: 28106129 *Co-First Authors
  • Blum K, Drews J, Breuer CK (2018) “Tissue Engineered Heart Valves: A Call for Mechanistic Studies” Tissue Engineering Part B: Reviews 24(3):240-253 PMID: 29327671
  • Agarwal R*, Blum K*, Musgrave A, Onwuka E, Yi T, Reinhardt J, Best C, Breuer C (2019) “Degradation and in vivo Evaluation of PCL, PCLA, and PLLA as Scaffold Sealant Polymers for Murine TEVGs” Regen Med 14(7):627-637 PMID: 31342857 *Co-First Authors
  • Morelli C, Castaldi L, Brown S, Streich L, Websdale A, Taberner F, Cerreti B, Barenghi A, Blum KM, Sawitzke J, Frank T, Steffens, Doleschall, Serrao J, Lechner S, Prevedel R, Heppenstall P (2020) “Identification of a novel population of peripheral sensory neuron that regulates blood pressure” BioRxiv
  • Hatoum H, Gooden S, Heitkemper M, Blum KM, Zakko J, Bocks M, Yi T, Wu YL, Wang Y, Breuer CK, Dasi LP (2020) “Fetal Transcatheter Trileaflet Heart Valve Hemodynamics: Implications of Scaling on Valve Mechanics and Turbulence” Ann Biomed Eng 48(6):1683-1693 PMID: 32052320
  • Blum K, Zakko J, Fong P, Maxfield M, Cleary M, Breuer C (2020) “Heart Valve Tissue Engineering” in Lanza Principles of Tissue Engineering, 5th ed. Academic Press, pp. 635-54
  • Drews J, Pepper V, Best C, [and 34 others, including Blum KM] (2020) “Spontaneous reversal of stenosis in tissue engineered vascular grafts”, Sci Trans Med 12(537) PMID: 32238576
  • Matsuzaki Y, Iwaki R, Reinhardt J, Chang Y, Miyamoto S, Kelly J, Zbinden J, Blum KM, Mirhaidari G, Ulziibayar A, Shoji T, Breuer C (2020) “The Effect of Pore Diameter on Neo-Tissue Formation in Electrospun Biodegradable Tissue Engineered Arterial Grafts in a Large Animal Model”, Acta Biomat 18:S1742-7061(20)30471-2 PMID: 32822820
  • Wu Y*, Szafron J*, Blum KM*, Zbinden J, Khosravi R, Best C, Reinhardt J, Zheng Q, Yi T, Shinoka T, Humphrey J, Breuer C, Wang Y (2020) "Electrospun Tissue engineered arterial graft thickness affects long-term composition and mechanics" Tiss Eng A PMID: 32854586 *Co-First Author
  • Zakko J*, Blum KM*, Drews J*, Wu L*, Hatoum H*, Russell M*, Gooden S, Heitkemper M, Conroy O, Kelly J, Carey S, Sacks M, Texter K, Ragsdale E, Strainic J, Bocks M, Wang Y, Dasi L, Armstrong A, Breuer C (2020) “Development of a Tissue Engineered Heart Valve for Percutaneous Transcatheter Delivery in a Fetal Large Animal Model”, JACC Bas to Trans Sci 29;5(8):815-828 PMID: 32875171 *Co-First Author
  • Matsuzaki Y, Miyamoto S, Miyachi H, Iwaki R, Shoji T, Blum KM, Chang Y, Kelly J, Reinhardt J, Nakayama H, Breuer C, Shinoka T (2020) “Improvement of Novel Small-Diameter Tissue Engineered Arterial Graft with Heparin Conjugation”, Ann Thor Surg S0003-4975(20)31473-9 PMID: 32946845
  • Zbinden J*, Blum KM*, Berman A*, Ramachandra AB, Szafron J, Kerr, K, Anderson J, Sangha G, Earl C, Nigh N, Mirhaidari G, Reinhardt J, Chang Y, Yi T, Smalley R, Gabriele P, Harris J, Humphrey J, Goergen C, Breuer CK (2020) “Effects of Braiding Parameters on Tissue Engineered Vascular Graft Development”, Adv Healthcare Mat 9(24):e2001093 PMID: 33063452 *Co-First Author
  • Mirhaidari G, Barker J, Zbinden J, Santerello B, Chang Y, Best C, Reinhardt J, Blum KM, Yi T, Breuer CK (2020) “Recipient Interleukin 10 Status is Critical for Preventing Tissue Engineered Vascular Graft Thrombosis” Adv Healthcare Mat 9(24):e2001094 PMID: 33073543
  • Blum KM, Mirhaidari G, Breuer CK (2021) “Tissue Engineering: Relevance to Neonatal Congenital Heart Disease” Semin Fetal Neonatal Med PMID: 33674254
  • Blum KM, Roby LC, Zbinden JC, Chang YC, Mirhaidari GJM, Reinhardt JW, Yi T, Barker JC, Breuer CK (2021) “Sex and Tamoxifen Confound Murine Experimental Studies in Cardiovascular Tissue Engineering” Nat Sci Rep

Long-term goals/aspirations

Become a good physician and engineer, and develop something that can change someone’s life for the better.

Post MSTP Training dream job

Become a Pediatric Cardiologist with my own regenerative medicine research laboratory and work with industry to get new technologies to patients.

Fun Facts

What you enjoy outside of school

Playing with Mackey, my border collie – poodle mix. Playing the drums. Playing board games and card games.

A talent you have always wanted

Any sort of balance/coordination/athletic ability for any sport.

Favorite book

The Harry Potter series or anything by Terry Pratchett

Favorite quote

If something is worth doing, it’s worth over-doing

Can’t live without

Angela, my wife.

If you weren’t in MSTP, what would you be doing now?

Either playing music or working in industry as a biomedical engineer

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